Which metabolic disorder is associated with the formation of kidney stones?

Gout is a metabolic disorder that is characterized by elevated levels of uric acid in the blood, which can lead to the formation of kidney stones, specifically uric acid stones. When uric acid levels become excessively high, the body can saturate with uric acid, leading to precipitation and crystallization. These uric acid crystals can accumulate in the kidneys, forming stones.

In the context of kidney stones, certain risk factors associated with gout, such as dehydration, high purine intake from foods (like red meat and seafood), and the body's difficulty in excreting uric acid, play a significant role in stone formation. Patients with gout, therefore, need to be vigilant about their uric acid levels and hydration status to prevent both gout flares and the subsequent risk of developing kidney stones.

Other metabolic disorders listed, such as diabetes, hypothyroidism, and hyperlipidemia, are not directly linked to the formation of kidney stones in the same way that gout is. While diabetes can cause other kidney-related issues, it does not specifically increase the risk of stone formation due to metabolic disturbances related to uric acid.