What is a potential consequence of untreated acute kidney injury?

Untreated acute kidney injury (AKI) can lead to the retention of waste products in the body. The kidneys play a crucial role in filtering waste and excess substances from the bloodstream, so when they are injured and their function declines, the ability to eliminate these waste products is impaired. This retention can lead to a buildup of substances like urea, creatinine, and other metabolic wastes, which can result in serious complications, including uremia. This state demands effective management to prevent further damage to the kidneys and to ensure that the body is able to maintain homeostasis.

Other potential outcomes of untreated AKI would not result in the same implications as waste retention. Improved kidney function and enhanced urinary output are unlikely scenarios when the kidneys are not functioning properly. An increase in blood volume would not directly link to AKI without additional compensatory mechanisms, as impaired function often leads to fluid imbalances rather than an increase in volume.