What does acute renal failure (ARF) primarily result in?

Acute renal failure (ARF), which is also known as acute kidney injury (AKI), primarily results in severely decreased urine production, a condition referred to as oliguria. In ARF, the kidneys lose their ability to filter waste and excess fluid from the blood effectively, which can lead to retention of fluid and waste products in the body.

As the kidneys become damaged due to various reasons, such as ischemia, nephrotoxins, or obstruction, their functional capacity is compromised. This impairment often manifests in a significant reduction in urine output, sometimes to a nearly complete cessation of尿. Monitoring urine output is a critical aspect of assessing kidney function during episodes of ARF.

While ARF can lead to an increase in creatinine levels due to the kidneys' diminished ability to excrete this waste product, the hallmark observable feature is the marked decrease in urine production. Therefore, understanding the physiological changes that occur in the kidneys during ARF is essential for proper diagnosis and treatment.